Microarray-based discovery and genotyping of viral pathogens

2^nd World Congress Virology and Infectious disease

Date: September 3-4, 2019

Venue: London, UK

URL: https://bit.ly/2QeWHY3

 Microarray-based discovery and genotyping of viral pathogens

The detection of viral pathogens is of vital importance in biology, medicine, and agriculture. Unfortunately, existing techniques to screen for a broad spectrum of viruses suffer from severe limits.

To facilitate the great and unbiased analysis of viral prevalence during a given biological setting, we've got developed a genomic strategy for extremely parallel viral screening.

The cornerstone of this approach may be a long oligonucleotide (70-mer) deoxyribonucleic acid microarray capable of at the same time detective work many viruses.

Victimization virally infected cell cultures, we tend to were able to expeditiously find and establish several various viruses.

Connected viral serotypes might be distinguished by the distinctive pattern of coupling generated by every virus. 

What is more, by choosing microarray parts derived from extremely preserved regions inside viral families, individual viruses that weren't expressly pictured on the microarray were still detected, raising the likelihood that this approach might be used for virus discovery.

Finally, by employing a random PCR amplification strategy in conjunction with the microarray, we tend to were able to find multiple viruses in human metabolism specimens while not the utilization of sequence-specific or degenerate primers.

This methodology is flexible and greatly expands the spectrum of detectable viruses during a single assay whereas at the same time providing the potential to discriminate among viral subtypes.

To know more about virology and infectious disease, attend an event on General Virology at Virology conference

Contact detailsClara Charlotte
Program Manager | virology 2019
Email:virology@microbioconferences.com
Phone: +44 20 3769 1755